C12orf54

Across TCGA cell cohorts, C12orf54 RNA expression is significantly associated with the RNA expression of many other genes, with 3,230 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible C12orf54-associated genes across cancer lineages are C17orf99, LORICRIN, and PGLYRP3. Each is linked with C12orf54 in more than 5 cancer types. Because this analysis shows association rather than direction, both C12orf54-to-partner and partner-to-C12orf54 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C12orf54 versus C17orf99 in URINARY_TRACT, with a Pearson correlation of 0.49.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C12orf54→partner) and Y-score (partner→C12orf54) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	C17orf99 →	+1.056	+1.221	<.001	<.001	3	6
BLOOD_Lymphoma	LORICRIN →	+0.689	+1.105	.002	<.001	3	5
STOMACH	PGLYRP3 →	+0.589	+0.689	.004	<.001	3	5
STOMACH	PGLYRP4 →	+0.988	+0.815	.001	<.001	3	5
SKIN	LCE3E →	+0.290	+0.928	.006	<.001	3	4
BLOOD_Lymphoma	LCE1C →	+0.681	+1.756	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,230 associations by consensus.

C12orf54 vs C17orf99 — URINARY_TRACT

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