C12orf54

Across TCGA cell cohorts, C12orf54 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible C12orf54-associated genes across cancer lineages are OR2J2 and C3orf56. Each is linked with C12orf54 in more than 1 cancer types. Because this analysis shows association rather than direction, both C12orf54-to-partner and partner-to-C12orf54 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2J2 grouped by C12orf54-low versus C12orf54-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C12orf54→partner) and Y-score (partner→C12orf54) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	OR2J2 →	+0.013	+4.977	<.001	.007	3	1
SKIN	C3orf56 →	+0.006	+4.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

OR2J2 by C12orf54 expression — SKIN

Explore this box plot interactively →