C12orf54

Across TCGA cell cohorts, C12orf54 mutation is significantly associated with the mutation status of many other genes, with 25 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible C12orf54-associated genes across cancer lineages are LINC01559, PRKN, and CDHR4. Each is linked with C12orf54 in more than 1 cancer types. Because this analysis shows association rather than direction, both C12orf54-to-partner and partner-to-C12orf54 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01559 grouped by C12orf54-low versus C12orf54-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C12orf54→partner) and Y-score (partner→C12orf54) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	LINC01559 →	+4.239	+5.053	.007	.007	1	1
SKIN	PRKN →	+5.824	+5.824	.002	.002	1	1
SKIN	CDHR4 →	+4.239	+5.053	.007	.007	1	1
SKIN	ZNF665 →	+4.824	+5.392	.004	.004	1	1
SKIN	CFAP299 →	+4.824	+5.392	.004	.004	1	1
SKIN	SEC14L6 →	+4.824	+5.392	.004	.004	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

LINC01559 by C12orf54 expression — SKIN

Explore this box plot interactively →