C12orf40

Across TCGA cell cohorts, C12orf40 RNA expression is significantly associated with the mutation status of many other genes, with 423 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible C12orf40-associated genes across cancer lineages are XIRP2, CUBN, and GPLD1. Each is linked with C12orf40 in more than 3 cancer types. Because this analysis shows association rather than direction, both C12orf40-to-partner and partner-to-C12orf40 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, XIRP2 grouped by C12orf40-low versus C12orf40-high in OVARY.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C12orf40→partner) and Y-score (partner→C12orf40) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	XIRP2 →	+4.029	+0.011	.009	<.001	3	4
LUNG_SCLC	CUBN →	+2.099	+0.016	<.001	<.001	3	3
OVARY	GPLD1 →	+2.859	+0.007	.008	.003	3	3
OVARY	PLXNC1 →	+4.444	+0.010	.001	<.001	3	3
OVARY	PDE4DIP →	+2.707	+0.008	<.001	<.001	3	3
SOFT_TISSUE	LRRC7 →	+4.930	+0.383	.008	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 423 associations by consensus.

XIRP2 by C12orf40 expression — OVARY

Explore this box plot interactively →