C12orf29

Across TCGA patient cohorts, C12orf29 mutation is significantly associated with the RNA expression of many other genes, with 2,538 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C12orf29-associated genes across cancer lineages are SENP3-EIF4A1, IGLV2-8, and MYO19. Each is linked with C12orf29 in more than 1 cancer types. Because this analysis shows association rather than direction, both C12orf29-to-partner and partner-to-C12orf29 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SENP3-EIF4A1 grouped by C12orf29-low versus C12orf29-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C12orf29→partner) and Y-score (partner→C12orf29) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SENP3-EIF4A1 →	+0.205	+3.684	<.001	.001	3	1
UCEC	IGLV2-8 →	+2.292	+2.321	<.001	.006	3	1
UCEC	MYO19 →	+0.670	+3.000	<.001	.001	3	1
UCEC	MIR6803 →	+0.121	+4.478	<.001	.003	3	1
UCEC	GGNBP2 →	+0.449	+3.470	.002	.002	3	1
UCEC	H2BC10 →	+0.735	+3.716	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,538 associations by consensus.

SENP3-EIF4A1 by C12orf29 expression — UCEC

Explore this box plot interactively →