C12orf29

Across TCGA pan-cancer cohorts, C12orf29 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated C12orf29 data layer compared with 2 for mutation status and 5 for mass-spec protein.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher C12orf29 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated C12orf29 expression acts as an unfavorable survival marker, although some lineages such as KIRC and LGG show a favorable association.

KIRP, KICH, and LIHC are the cancer types where C12orf29 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	OS	Quartile	All	0.470	0.794	<.001	127	view →
KICH	DFS	Tertile	All	0.615	1.000	.001	62	view →
LIHC	DFS	Tertile	All	0.433	0.609	<.001	51	view →
LUAD	OS	Tertile	All	0.219	0.434	.001	51	view →
UVM	DFS	Quartile	III,IV	0.170	0.823	.001	48	view →
ACC	OS	Quartile	All	0.718	0.967	.001	45	view →
KIRC	DFS	Tertile	All	0.768	0.482	<.001	30	view →
DLBC	DFS	Tertile	III,IV	0.171	0.984	.007	20	view →
UCEC	DFS	Median	All	0.795	0.874	.005	18	view →
THCA	DFS	Tertile	II,III,IV	0.861	0.955	.009	18	view →
STAD	OS	Median	All	0.375	0.656	.022	18	view →
CESC	OS	Median	III,IV	0.215	0.776	.011	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

C12orf29–KIRP (OS)

Open the KIRP breakdown →