C11orf40

Across TCGA patient cohorts, C11orf40 mutation is significantly associated with the RNA expression of many other genes, with 612 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C11orf40-associated genes across cancer lineages are LINC00265-2P, LINC01399, and SLC10A7. Each is linked with C11orf40 in more than 1 cancer types. Because this analysis shows association rather than direction, both C11orf40-to-partner and partner-to-C11orf40 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC00265-2P grouped by C11orf40-low versus C11orf40-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C11orf40→partner) and Y-score (partner→C11orf40) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	LINC00265-2P →	+0.084	+5.137	<.001	<.001	3	2
UCEC	LINC01399 →	+0.291	+2.378	<.001	.002	3	2
UCEC	SLC10A7 →	+0.432	+2.595	.009	.006	3	2
SKCM	OR2W4P →	+0.022	+4.634	<.001	.003	3	2
SKCM	DSCR10 →	+0.577	+3.006	<.001	.006	3	2
BRCA	LINC02423 →	+0.078	+7.731	.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 612 associations by consensus.

LINC00265-2P by C11orf40 expression — LUAD

Explore this box plot interactively →