C10orf71

Across TCGA patient cohorts, C10orf71 mutation is significantly associated with the total protein of many other genes, with 38 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C10orf71-associated genes across cancer lineages are INPP4B, Annexin-1, and Ku80. Each is linked with C10orf71 in more than 2 cancer types. Because this analysis shows association rather than direction, both C10orf71-to-partner and partner-to-C10orf71 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, INPP4B grouped by C10orf71-low versus C10orf71-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C10orf71→partner) and Y-score (partner→C10orf71) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	INPP4B →	-0.472	-2.991	.014	.036	3	3
UCEC	Annexin-1 →	+0.448	+2.522	.006	<.001	3	3
UCEC	Ku80 →	+0.283	+2.080	<.001	<.001	3	2
UCEC	PDCD4 →	-0.482	-2.415	<.001	.002	3	2
UCEC	AMPK_pT172 →	+0.285	+1.013	.025	.047	3	2
UCEC	TFRC →	+0.421	+2.807	.010	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 38 associations by consensus.

INPP4B by C10orf71 expression — COAD

Explore this box plot interactively →