C10orf71

Across TCGA cell cohorts, C10orf71 mutation is significantly associated with the RNA expression of many other genes, with 761 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible C10orf71-associated genes across cancer lineages are MRPS18C, CXorf51A, and CTSZ. Each is linked with C10orf71 in more than 1 cancer types. Because this analysis shows association rather than direction, both C10orf71-to-partner and partner-to-C10orf71 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MRPS18C grouped by C10orf71-low versus C10orf71-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C10orf71→partner) and Y-score (partner→C10orf71) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	MRPS18C →	+0.651	+3.169	<.001	.006	3	2
STOMACH	CXorf51A →	+0.396	+3.152	<.001	.002	3	2
LARGE_INTESTINE	CTSZ →	-0.931	-3.459	.002	<.001	3	2
LARGE_INTESTINE	MRPL19 →	+0.556	+1.850	<.001	.006	3	2
LARGE_INTESTINE	KDSR →	+0.753	+2.364	<.001	<.001	3	2
LARGE_INTESTINE	TAF4B →	+0.783	+3.584	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 761 associations by consensus.

MRPS18C by C10orf71 expression — LUNG_SCLC

Explore this box plot interactively →