C10orf120

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, C10orf120 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C10orf120-associated genes across cancer lineages are LMNTD1, OR2J2, and TBC1D3. Each is linked with C10orf120 in more than 1 cancer types. Because this analysis shows association rather than direction, both C10orf120-to-partner and partner-to-C10orf120 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C10orf120→partner) and Y-score (partner→C10orf120) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINELMNTD1 →+0.155+3.969<.001.00231
LARGE_INTESTINEOR2J2 →+0.010+3.632.005.00331
LARGE_INTESTINETBC1D3 →+0.061+3.688<.001.00231
BLOOD_LeukemiaZP2 →+0.122+3.824<.001.00131
BLOOD_LeukemiaFBP2 →+0.170+4.091.009.00231
BLOOD_LeukemiaFRMD1 →+0.108+3.847<.001.00431
Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

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