Across TCGA pan-cancer cohorts, C10orf120 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of C10orf120’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where C10orf120 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types C10orf120 is over-expressed in tumor, although a few such as ESCA show the opposite, repressed pattern.

LUSC and ESCA are the cancer types where C10orf120 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in C10orf120 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	All	All	+0.058	.038	2	view →
ESCA	All	All	−0.208	.027	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: C10orf120 RNA expression & survival · all C10orf120 data types