BUD31

Across TCGA patient cohorts, BUD31 mutation is significantly associated with the RNA expression of many other genes, with 101 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BUD31-associated genes across cancer lineages are NIFKP2, LINC02358, and RNU6-711P. Each is linked with BUD31 in more than 1 cancer types. Because this analysis shows association rather than direction, both BUD31-to-partner and partner-to-BUD31 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NIFKP2 grouped by BUD31-low versus BUD31-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BUD31→partner) and Y-score (partner→BUD31) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	NIFKP2 →	+0.054	+5.037	<.001	.009	3	1
SKCM	LINC02358 →	+0.098	+6.080	<.001	.002	3	1
SKCM	RNU6-711P →	+0.407	+5.292	<.001	.006	3	1
BLCA	GPHB5 →	+0.091	+5.411	.003	.005	3	1
BLCA	IGLJ7 →	+0.781	+5.177	<.001	.007	3	1
UCEC	TMEM245 →	+0.641	+3.332	.004	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 101 associations by consensus.

NIFKP2 by BUD31 expression — SKCM

Explore this box plot interactively →