BUD31

Across TCGA cell cohorts, BUD31 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,291 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible BUD31-associated GO terms across cancer lineages are L-serine biosynthetic process, tRNA dihydrouridine synthesis, and Negative regulation of stress granule assembly. Each is linked with BUD31 in more than 10 cancer types. Because this analysis shows association rather than direction, both BUD31-to-partner and partner-to-BUD31 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, L-serine biosynthetic process grouped by BUD31-low versus BUD31-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BUD31→partner) and Y-score (partner→BUD31) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	L-serine biosynthetic process →	+0.123	+0.528	<.001	<.001	2	11
KIDNEY	tRNA dihydrouridine synthesis →	+0.119	+0.545	<.001	.007	2	10
BLOOD_Myeloma	Negative regulation of stress granule assembly →	+0.094	+0.759	.005	.003	3	8
UPPER_AERODIGESTIVE_TRACT	Peptidyl-glutamic acid carboxylation →	+0.112	+1.107	<.001	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	Protein carboxylation →	+0.112	+1.107	<.001	<.001	3	8
SOFT_TISSUE	Regulation of telomeric D-loop disassembly →	+0.119	+0.813	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,291 associations by consensus.

L-serine biosynthetic process by BUD31 expression — BLOOD_Leukemia

Explore this box plot interactively →