BUB3P1

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, BUB3P1 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated BUB3P1 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher BUB3P1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated BUB3P1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and OV show a favorable association.

HNSC, UCS, and CESC are the cancer types where BUB3P1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
HNSCOSTertileIII,IV0.8300.696.002132view →
UCSDFSTertileIV0.1320.718.00272view →
CESCOSTertileIII,IV0.4750.787.01272view →
STADOSQuartileII,III,IV0.4590.829.00348view →
ACCDFSTertileAll0.4080.809.00236view →
THCADFSTertileII,III,IV0.8120.935.01924view →
UVMOSTertileAll0.2920.674.03518view →
OVOSTertileIV0.8180.490<.00118view →
LUSCOSTertileIII,IV0.4870.812.02112view →
PRADDFSTertileAll0.9750.750.03412view →
LIHCOSTertileII,III,IV0.2550.768.0189view →
ESCAOSMedianIV0.7380.293.0486view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

Exploration