BUB3 mitotic checkpoint protein pseudogene 1Genealiases: []
Q-omics provides the consensus-scored BUB3P1 profile across patient tissues and cancer cell-line models. BUB3P1 expression is associated with patient survival in 15 of 34 cancer types, with the highest sampling consensus in HNSC. Among the 18 cancer types available for tumor–normal comparison, BUB3P1 is differentially expressed in 6, with the highest sampling consensus in LUAD. Additionally, BUB3P1 RNA expression shows 6,424 significant protein co-abundance associations, with the highest sampling consensus in OV. Together, these results highlight HNSC, LUAD, and OV as cancer lineages where BUB3P1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for BUB3P1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes BUB3P1 survival associations across molecular data types. BUB3P1 RNA expression shows survival associations in the most cancer types (15). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible BUB3P1 RNA expression–survival associations across cancer types. High BUB3P1 expression shows unfavorable associations in CESC, UCS, STAD, ACC and THCA, but favorable associations in HNSC. The HNSC Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p = .002). Together, the overview and detailed table identify HNSC as the clearest survival context for BUB3P1 RNA expression.
This table summarizes BUB3P1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 6. The strongest signals are observed in LUAD for RNA.
This table ranks reproducible tumor–normal expression differences for BUB3P1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. BUB3P1 shows lower tumor expression in THCA and UCEC and higher tumor expression in LUAD, COAD, STAD and HNSC. The LUAD box plot shows higher BUB3P1 RNA expression in tumor versus normal tissue (log2 FC = +0.039, t-test p = .001).
This table shows molecular features associated with BUB3P1 in patient tissues and cancer cell lines. In patient samples, BUB3P1 shows the broadest associations at the RNA and protein expression levels, with OV recurring as the lineage with the largest associated feature set.
