BUB1B

Across TCGA cell cohorts, BUB1B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,895 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible BUB1B-associated GO terms across cancer lineages are Regulation of G2/M transition of mitotic cell cycle, Regulation of cell cycle G2/M phase transition, and Nuclear division. Each is linked with BUB1B in more than 19 cancer types. Because this analysis shows association rather than direction, both BUB1B-to-partner and partner-to-BUB1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of G2/M transition of mitotic cell cycle grouped by BUB1B-low versus BUB1B-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BUB1B→partner) and Y-score (partner→BUB1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Regulation of G2/M transition of mitotic cell cycle →	+0.107	+1.557	<.001	<.001	3	20
URINARY_TRACT	Regulation of cell cycle G2/M phase transition →	+0.093	+1.386	<.001	<.001	3	20
OESOPHAGUS	Nuclear division →	+0.092	+1.183	.001	.002	3	20
BLOOD_Myeloma	Interstrand cross-link repair →	+0.115	+1.615	<.001	<.001	3	20
SOFT_TISSUE	Mitotic DNA integrity checkpoint signaling →	+0.110	+1.674	<.001	<.001	3	20
OESOPHAGUS	Spindle elongation →	+0.235	+1.274	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,895 associations by consensus.

Regulation of G2/M transition of mitotic cell cycle by BUB1B expression — URINARY_TRACT

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