BUB1B-PAK6

Across TCGA patient cohorts, BUB1B-PAK6 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,787 significant associations in total. THCA shows the largest number of these associations.

The most reproducible BUB1B-PAK6-associated GO terms across cancer lineages are Positive regulation of translation in response to stress, Ribosome-associated ubiquitin-dependent protein catabolic process, and Obsolete histone methylation. Each is linked with BUB1B-PAK6 in more than 19 cancer types. Because this analysis shows association rather than direction, both BUB1B-PAK6-to-partner and partner-to-BUB1B-PAK6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of translation in response to stress grouped by BUB1B-PAK6-low versus BUB1B-PAK6-high in THYM.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BUB1B-PAK6→partner) and Y-score (partner→BUB1B-PAK6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THYM	Positive regulation of translation in response to stress →	+0.105	+0.094	<.001	<.001	3	19
THYM	Ribosome-associated ubiquitin-dependent protein catabolic process →	+0.078	+0.066	<.001	<.001	3	18
DLBC	Obsolete histone methylation →	+0.060	+0.015	.005	.008	1	20
THYM	Regulation of translational initiation in response to stress →	+0.067	+0.052	<.001	<.001	3	18
DLBC	Glycerophospholipid biosynthetic process →	+0.044	+0.018	.004	.003	3	18
THYM	Regulation of cytoplasmic translational initiation →	+0.061	+0.063	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,787 associations by consensus.

Positive regulation of translation in response to stress by BUB1B-PAK6 expression — THYM

Explore this box plot interactively →