BTNL8

Across TCGA patient cohorts, BTNL8 mutation is significantly associated with the RNA expression of many other genes, with 1,628 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BTNL8-associated genes across cancer lineages are SNF8, APCDD1, and MIR130A. Each is linked with BTNL8 in more than 2 cancer types. Because this analysis shows association rather than direction, both BTNL8-to-partner and partner-to-BTNL8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNF8 grouped by BTNL8-low versus BTNL8-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BTNL8→partner) and Y-score (partner→BTNL8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	SNF8 →	+0.235	+1.199	.001	.005	3	3
UCEC	APCDD1 →	-1.145	-3.896	<.001	<.001	3	3
LUSC	MIR130A →	+0.348	+3.169	.009	.006	3	3
UCEC	E2F1 →	+0.632	+2.469	.002	.001	3	3
UCEC	MRPL37 →	+0.344	+2.169	.005	<.001	3	3
UCEC	TRAJ11 →	+0.328	+1.611	.003	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,628 associations by consensus.

SNF8 by BTNL8 expression — SKCM

Explore this box plot interactively →