BTNL8

Across TCGA cell cohorts, BTNL8 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible BTNL8-associated genes across cancer lineages are OR10W1, OR4F4, and OR13G1. Each is linked with BTNL8 in more than 1 cancer types. Because this analysis shows association rather than direction, both BTNL8-to-partner and partner-to-BTNL8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10W1 grouped by BTNL8-low versus BTNL8-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BTNL8→partner) and Y-score (partner→BTNL8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	OR10W1 →	+0.010	+4.781	<.001	.003	3	1
LARGE_INTESTINE	OR4F4 →	+0.017	+4.273	.001	.006	3	1
LARGE_INTESTINE	OR13G1 →	+0.024	+4.415	<.001	.007	3	1
LARGE_INTESTINE	OR6Q1 →	+0.022	+5.022	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

OR10W1 by BTNL8 expression — BREAST

Explore this box plot interactively →