BTN2A3P

Across TCGA patient cohorts, BTN2A3P mutation is significantly associated with the total protein of many other genes, with 17 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BTN2A3P-associated genes across cancer lineages are EGFR_pY1068, VHL, and PCNA. Each is linked with BTN2A3P in more than 1 cancer types. Because this analysis shows association rather than direction, both BTN2A3P-to-partner and partner-to-BTN2A3P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EGFR_pY1068 grouped by BTN2A3P-low versus BTN2A3P-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BTN2A3P→partner) and Y-score (partner→BTN2A3P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1068 →	-0.229	-2.000	.020	.010	3	2
UCEC	VHL →	-0.731	-2.000	.006	.010	3	2
LUAD	PCNA →	+0.208	+3.012	.026	.018	3	1
LUAD	PKC-a_pS657 →	-0.352	-3.000	.041	.036	2	2
LUAD	PREX1 →	-0.221	-3.000	.013	.036	3	1
UCEC	eIF4E →	+0.168	+2.183	.042	.033	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

EGFR_pY1068 by BTN2A3P expression — UCEC

Explore this box plot interactively →