BTN2A3P

Across TCGA pan-cancer cohorts, BTN2A3P RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of BTN2A3P’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where BTN2A3P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types BTN2A3P is over-expressed in tumor, although a few such as KICH and BRCA show the opposite, repressed pattern.

HNSC, KIRC, and COAD are the cancer types where BTN2A3P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in BTN2A3P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Female	IV	+1.026	<.001	12	view →
KIRC	Male	All	+0.650	<.001	11	view →
COAD	All	IV	+0.867	<.001	10	view →
LIHC	Female	II,III,IV	+0.477	<.001	8	view →
KIRP	All	All	+0.440	.001	7	view →
KICH	Female	All	−0.967	<.001	6	view →
BLCA	Female	All	+0.876	.002	6	view →
READ	All	II,III,IV	+0.659	.002	6	view →
STAD	All	II,III,IV	+0.560	.001	6	view →
CHOL	Male	All	+1.063	<.001	4	view →
BRCA	Female	All	−0.312	<.001	4	view →
THCA	All	II,III,IV	−0.343	.014	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

BTN2A3P–HNSC

Open the HNSC breakdown →