BTN2A2

Across TCGA patient cohorts, BTN2A2 protein abundance is significantly associated with the RNA expression of many other genes, with 3,326 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible BTN2A2-associated genes across cancer lineages are BET1, NPRL2, and STAT1. Each is linked with BTN2A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both BTN2A2-to-partner and partner-to-BTN2A2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BTN2A2 versus BET1 in CCRCC, with a Pearson correlation of -0.87.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BTN2A2→partner) and Y-score (partner→BTN2A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	BET1 →	-0.467	-1.434	<.001	<.001	3	1
CCRCC	NPRL2 →	-0.519	-1.836	.006	<.001	3	1
CCRCC	STAT1 →	+1.484	+1.434	.005	<.001	3	1
CCRCC	VPREB3 →	+0.740	+1.633	<.001	.001	3	1
CCRCC	FIBCD1 →	+1.950	+1.686	.007	<.001	3	1
CCRCC	TRIM22 →	+0.857	+1.434	.005	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,326 associations by consensus.

BTN2A2 vs BET1 — CCRCC

Explore this scatter interactively →