BTF3P11

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, BTF3P11 mutation is significantly associated with the RNA expression of many other genes, with 21 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible BTF3P11-associated genes across cancer lineages are IGHD6-19, LINC00265-2P, and TAB2-AS1. Each is linked with BTF3P11 in more than 1 cancer types. Because this analysis shows association rather than direction, both BTF3P11-to-partner and partner-to-BTF3P11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IGHD6-19 grouped by BTF3P11-low versus BTF3P11-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BTF3P11→partner) and Y-score (partner→BTF3P11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECIGHD6-19 →+2.519+5.420<.001.00531
UCECLINC00265-2P →+0.089+5.031<.001.00931
UCECTAB2-AS1 →+0.179+5.133.002.00831
UCECMTND4P7 →+0.433+5.621.004.00431
UCECTRAV37 →+0.294+5.420<.001.00531
SKCMRNA5SP307 →+0.385+4.771<.001.00631
Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

IGHD6-19 by BTF3P11 expression — UCEC

Box plot of IGHD6-19 in BTF3P11-low vs BTF3P11-high samples in UCEC.

Explore this box plot interactively →

Exploration