Across TCGA patient cohorts, BTBD6 mutation is significantly associated with the RNA expression of many other genes, with 1,028 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BTBD6-associated genes across cancer lineages are RNU6-1249P, RN7SL248P, and LARP1BP3. Each is linked with BTBD6 in more than 1 cancer types. Because this analysis shows association rather than direction, both BTBD6-to-partner and partner-to-BTBD6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BTBD6→partner) and Y-score (partner→BTBD6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU6-1249P →	+0.335	+5.332	<.001	.002	3	2
UCEC	RN7SL248P →	+0.066	+3.307	<.001	.003	3	2
HNSC	LARP1BP3 →	+0.053	+5.241	.009	.007	3	2
PRAD	MIR448 →	+0.283	+7.939	<.001	.008	3	1
PRAD	RNU6-369P →	+0.303	+7.939	<.001	.008	3	1
PRAD	RNU6-66P →	+0.298	+7.939	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,028 associations by consensus.

Exploration

BTBD6 survival (RNA) · tumor vs normal (RNA) · all BTBD6 data types