Across TCGA patient cohorts, BSPH1 mutation is significantly associated with the RNA expression of many other genes, with 251 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BSPH1-associated genes across cancer lineages are IGKV2OR2-1, CTHRC1P1, and IGHV3OR16-13. Each is linked with BSPH1 in more than 1 cancer types. Because this analysis shows association rather than direction, both BSPH1-to-partner and partner-to-BSPH1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BSPH1→partner) and Y-score (partner→BSPH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	IGKV2OR2-1 →	+0.699	+2.326	<.001	.008	3	1
UCEC	CTHRC1P1 →	+0.111	+3.279	.003	.006	3	1
UCEC	IGHV3OR16-13 →	+0.766	+3.118	.001	.002	3	1
UCEC	IGKV2-40 →	+0.734	+2.994	<.001	.003	3	1
UCEC	RN7SL478P →	+0.290	+3.161	<.001	<.001	3	1
UCEC	IGKV1OR-2 →	+0.225	+2.656	.002	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 251 associations by consensus.

Exploration

BSPH1 survival (RNA) · tumor vs normal (RNA) · all BSPH1 data types