BRWD1-IT1

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, BRWD1-IT1 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,893 significant associations in total. GBM shows the largest number of these associations.

The most reproducible BRWD1-IT1-associated proteins across cancer lineages are RBM42, PRCC, and SRSF1. Each is linked with BRWD1-IT1 in more than 3 cancer types. Because this analysis shows association rather than direction, both BRWD1-IT1-to-partner and partner-to-BRWD1-IT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BRWD1-IT1 versus RBM42 in LSCC, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (BRWD1-IT1→partner) and Y-score (partner→BRWD1-IT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCRBM42 →+0.304+0.609<.001<.00134
GBMPRCC →+0.319+0.481<.001<.00134
GBMSRSF1 →+0.491+0.517<.001<.00134
LSCCSON →+0.218+0.614<.001<.00134
LSCCSAP18 →+0.271+0.558<.001<.00134
GBMHNRNPL →+0.221+0.499<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 9,893 associations by consensus.

BRWD1-IT1 vs RBM42 — LSCC

Per-sample scatter of BRWD1-IT1 vs RBM42 in LSCC (Pearson r = 0.45).

Explore this scatter interactively →

Exploration