BRWD1-IT1

Across TCGA pan-cancer cohorts, BRWD1-IT1 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of BRWD1-IT1’s most consistent transcriptional readouts.

The strongest signal is observed in prostate adenocarcinoma (PRAD), where BRWD1-IT1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types BRWD1-IT1 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

PRAD, CHOL, and KICH are the cancer types where BRWD1-IT1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in BRWD1-IT1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
PRAD	All	All	+0.099	.041	2	view →
CHOL	All	All	+0.172	.040	1	view →
KICH	Female	All	−0.092	.014	1	view →
KIRC	Female	II,III,IV	+0.050	.024	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

BRWD1-IT1–PRAD

Open the PRAD breakdown →