BRWD1-IT1

Across TCGA pan-cancer cohorts, BRWD1-IT1 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated BRWD1-IT1 data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher BRWD1-IT1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated BRWD1-IT1 expression acts as an unfavorable survival marker, although some lineages such as UCS and BRCA show a favorable association.

UCS, ESCA, and CHOL are the cancer types where BRWD1-IT1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	OS	Tertile	II,III,IV	0.698	0.217	<.001	108	view →
ESCA	DFS	Tertile	II,III,IV	0.408	0.616	.006	35	view →
CHOL	OS	Tertile	III,IV	0.275	0.886	.045	18	view →
SARC	OS	Tertile	All	0.714	0.863	.001	18	view →
PRAD	DFS	Tertile	All	0.678	0.803	<.001	18	view →
ACC	DFS	Quartile	II,III,IV	0.420	0.683	.004	15	view →
BRCA	OS	Quartile	IV	0.786	0.235	.017	9	view →
THYM	OS	Tertile	III,IV	0.615	1.000	.019	9	view →
READ	DFS	Tertile	IV	0.283	0.697	.003	9	view →
PCPG	OS	Tertile	All	0.701	0.964	.037	9	view →
KICH	DFS	Quartile	III,IV	0.058	0.777	.020	8	view →
KIRC	DFS	Quartile	IV	0.327	0.626	.004	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

BRWD1-IT1–UCS (OS)

Open the UCS breakdown →