BRWD1-IT1

Across TCGA patient cohorts, BRWD1-IT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,637 significant associations in total. STAD shows the largest number of these associations.

The most reproducible BRWD1-IT1-associated GO terms across cancer lineages are Positive regulation of DNA repair, Nucleotide-excision repair, and 3'-UTR-mediated mRNA stabilization. Each is linked with BRWD1-IT1 in more than 20 cancer types. Because this analysis shows association rather than direction, both BRWD1-IT1-to-partner and partner-to-BRWD1-IT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA repair grouped by BRWD1-IT1-low versus BRWD1-IT1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BRWD1-IT1→partner) and Y-score (partner→BRWD1-IT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of DNA repair →	+0.046	+0.339	<.001	<.001	3	21
STAD	Nucleotide-excision repair →	+0.045	+0.328	<.001	<.001	3	21
ESCA	3'-UTR-mediated mRNA stabilization →	+0.052	+0.270	<.001	<.001	3	20
STAD	Protein-RNA complex organization →	+0.051	+0.332	<.001	<.001	3	19
STAD	Protein localization to cytoplasmic stress granule →	+0.083	+0.350	<.001	<.001	3	19
STAD	Regulation of DNA repair →	+0.046	+0.291	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,637 associations by consensus.

Positive regulation of DNA repair by BRWD1-IT1 expression — STAD

Explore this box plot interactively →