BROX

Across TCGA patient cohorts, BROX RNA expression is significantly associated with the protein abundance of many other proteins, with 10,736 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible BROX-associated proteins across cancer lineages are BPNT1, IRF2BP2, and PRUNE1. Each is linked with BROX in more than 5 cancer types. Because this analysis shows association rather than direction, both BROX-to-partner and partner-to-BROX results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BROX versus BPNT1 in BRCA, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (BROX→partner) and Y-score (partner→BROX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	BPNT1 →	+0.385	+0.534	<.001	<.001	3	6
OV	IRF2BP2 →	+0.318	+0.410	.009	.001	3	6
LSCC	PRUNE1 →	+0.389	+0.427	<.001	<.001	3	5
OV	EGLN1 →	+0.435	+0.365	<.001	.003	3	5
UCEC	RPRD2 →	+0.272	+0.813	<.001	<.001	3	5
UCEC	SCAMP3 →	+0.335	+0.735	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,736 associations by consensus.

BROX vs BPNT1 — BRCA

Explore this scatter interactively →