BRMS1L

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, BRMS1L mutation is significantly associated with the RNA expression of many other genes, with 1,600 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BRMS1L-associated genes across cancer lineages are RNU6ATAC29P, RNA5SP504, and RN7SL248P. Each is linked with BRMS1L in more than 1 cancer types. Because this analysis shows association rather than direction, both BRMS1L-to-partner and partner-to-BRMS1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6ATAC29P grouped by BRMS1L-low versus BRMS1L-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BRMS1L→partner) and Y-score (partner→BRMS1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADRNU6ATAC29P →+0.397+4.807.001.00432
BRCARNA5SP504 →+0.403+8.055<.001.00732
UCECRN7SL248P →+0.059+3.137<.001.00532
BRCAMIR3118-3 →+0.558+8.471<.001.00531
UCECIMMP1L →+0.446+2.939.001<.00131
UCECSAA4 →-0.719-2.584.004.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,600 associations by consensus.

RNU6ATAC29P by BRMS1L expression — COAD

Box plot of RNU6ATAC29P in BRMS1L-low vs BRMS1L-high samples in COAD.

Explore this box plot interactively →

Exploration