Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts
Across TCGA patient cohorts, BRMS1L mutation is significantly associated with the RNA expression of many other genes, with 1,600 significant associations in total. UCEC shows the largest number of these associations.
The most reproducible BRMS1L-associated genes across cancer lineages are RNU6ATAC29P, RNA5SP504, and RN7SL248P. Each is linked with BRMS1L in more than 1 cancer types. Because this analysis shows association rather than direction, both BRMS1L-to-partner and partner-to-BRMS1L results are reported.
Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6ATAC29P grouped by BRMS1L-low versus BRMS1L-high in COAD.
mutation associated genes by consensus
Ranked by combined sampling and lineage consensus. X-score (BRMS1L→partner) and Y-score (partner→BRMS1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.