BRD9

Across TCGA patient cohorts, BRD9 mutation is significantly associated with the RNA expression of many other genes, with 3,754 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BRD9-associated genes across cancer lineages are RNU6-391P, RPS15AP3, and MIR4488. Each is linked with BRD9 in more than 2 cancer types. Because this analysis shows association rather than direction, both BRD9-to-partner and partner-to-BRD9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-391P grouped by BRD9-low versus BRD9-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BRD9→partner) and Y-score (partner→BRD9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNU6-391P →	+0.097	+3.900	<.001	.008	3	3
BLCA	RPS15AP3 →	+0.118	+5.788	<.001	.003	3	3
LUSC	MIR4488 →	+0.671	+5.093	<.001	.008	3	3
OV	ARL2BPP5 →	+0.097	+3.945	<.001	.005	3	2
UCEC	HDGFL2 →	+0.476	+2.263	<.001	<.001	3	2
SKCM	CTDSPL2P2 →	+0.048	+4.225	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,754 associations by consensus.

RNU6-391P by BRD9 expression — SKCM

Explore this box plot interactively →