BRD9

Across TCGA pan-cancer cohorts, BRD9 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated BRD9 data layer compared with 4 for mutation status and 6 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher BRD9 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated BRD9 expression acts as an unfavorable survival marker, although some lineages such as SCLC and HNSC show a favorable association.

COAD, ACC, and LIHC are the cancer types where BRD9 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Tertile	All	0.365	0.586	<.001	91	view →
ACC	OS	Median	All	0.413	0.810	<.001	89	view →
LIHC	OS	Median	All	0.402	0.591	<.001	77	view →
KICH	DFS	Median	All	0.679	1.000	.005	71	view →
SCLC	DFS	Quartile	II,III,IV	0.797	0.286	<.001	68	view →
KIRC	DFS	Quartile	All	0.500	0.700	<.001	39	view →
CESC	DFS	Median	All	0.663	0.810	.001	32	view →
HNSC	DFS	Median	IV	0.382	0.255	.006	28	view →
SARC	OS	Tertile	All	0.610	0.830	<.001	25	view →
UCEC	DFS	Quartile	IV	0.913	0.476	.006	24	view →
UVM	OS	Median	III,IV	0.281	1.000	.003	19	view →
UCS	OS	Quartile	III,IV	0.758	0.222	.012	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

BRD9–COAD (DFS)

Open the COAD breakdown →