BPIFB3

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, BPIFB3 mutation is significantly associated with the RNA expression of many other genes, with 1,555 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BPIFB3-associated genes across cancer lineages are RNU6-178P, KCND3-AS1, and EEF1E1-BLOC1S5. Each is linked with BPIFB3 in more than 2 cancer types. Because this analysis shows association rather than direction, both BPIFB3-to-partner and partner-to-BPIFB3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BPIFB3→partner) and Y-score (partner→BPIFB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMRNU6-178P →+0.350+2.463.001.00133
READKCND3-AS1 →+0.293+5.653<.001.00332
READEEF1E1-BLOC1S5 →+0.204+5.219<.001.00632
HNSCOR8I2 →+0.041+5.763<.001.00132
HNSCRNU6-269P →+0.271+5.339<.001.00332
READCDRT15P8 →+0.125+5.421<.001.00532
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,555 associations by consensus.

Exploration