BOLA2B

Across TCGA cell cohorts, BOLA2B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,675 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible BOLA2B-associated GO terms across cancer lineages are [2Fe-2S] cluster assembly, Regulation of extent of cell growth, and Iron-sulfur cluster assembly. Each is linked with BOLA2B in more than 16 cancer types. Because this analysis shows association rather than direction, both BOLA2B-to-partner and partner-to-BOLA2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, [2Fe-2S] cluster assembly grouped by BOLA2B-low versus BOLA2B-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BOLA2B→partner) and Y-score (partner→BOLA2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	[2Fe-2S] cluster assembly →	+0.186	+1.023	<.001	<.001	3	17
BREAST	Regulation of extent of cell growth →	-0.078	-1.068	<.001	<.001	3	14
LUNG_SCLC	Iron-sulfur cluster assembly →	+0.102	+0.938	<.001	<.001	3	14
LUNG_SCLC	Metallo-sulfur cluster assembly →	+0.102	+0.938	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Response to epidermal growth factor →	-0.130	-1.414	<.001	<.001	3	13
LARGE_INTESTINE	Schwann cell differentiation →	-0.114	-0.877	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,675 associations by consensus.

[2Fe-2S] cluster assembly by BOLA2B expression — LUNG_SCLC

Explore this box plot interactively →