BOLA2B

Across TCGA pan-cancer cohorts, BOLA2B RNA differs between tumor and matched normal tissue in 16 of 18 cancer types tested, making tumor–normal expression one of BOLA2B’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where BOLA2B RNA is more highly expressed in tumor relative to normal tissue. In most cancer types BOLA2B is over-expressed in tumor.

HNSC, BLCA, and STAD are the cancer types where BOLA2B tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in BOLA2B RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	IV	+0.582	<.001	12	view →
BLCA	Male	All	+0.946	<.001	11	view →
STAD	All	All	+0.669	<.001	9	view →
KIRC	Male	III,IV	+0.267	<.001	9	view →
LIHC	Male	II,III,IV	+0.671	<.001	8	view →
KIRP	All	II,III,IV	+0.556	<.001	8	view →
LUAD	Male	All	+0.445	<.001	7	view →
UCEC	All	All	+0.902	<.001	6	view →
LUSC	All	II,III,IV	+0.545	<.001	6	view →
BRCA	All	III,IV	+0.490	<.001	6	view →
COAD	All	All	+0.345	.012	5	view →
CHOL	Female	All	+0.809	<.001	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 16 lineages.

BOLA2B–HNSC

Open the HNSC breakdown →