BOLA2B

Across TCGA pan-cancer cohorts, BOLA2B RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated BOLA2B data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher BOLA2B RNA is associated with worse overall survival. In most high-consensus cancer types, elevated BOLA2B expression acts as an unfavorable survival marker, although some lineages such as CESC and SKCM show a favorable association.

UVM, KIRC, and CESC are the cancer types where BOLA2B RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Median	All	0.421	0.779	<.001	127	view →
KIRC	OS	Quartile	All	0.807	0.923	<.001	84	view →
CESC	DFS	Tertile	III,IV	0.803	0.262	.006	58	view →
ACC	OS	Median	All	0.671	0.917	<.001	47	view →
KIRP	OS	Median	All	0.537	0.919	<.001	42	view →
UCS	DFS	Median	IV	0.367	0.952	.001	36	view →
HNSC	DFS	Tertile	II,III,IV	0.249	0.523	.001	35	view →
SKCM	DFS	Quartile	IV	0.621	0.055	.010	24	view →
BRCA	OS	Median	IV	0.345	0.717	.014	20	view →
LIHC	OS	Quartile	III,IV	0.472	0.894	.004	18	view →
STAD	DFS	Median	All	0.604	0.706	.020	15	view →
BLCA	OS	Median	III,IV	0.657	0.477	.003	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

BOLA2B–UVM (OS)

Open the UVM breakdown →