BNIP3L

Across TCGA cell cohorts, BNIP3L RNA expression is significantly associated with the go_rna of many other GO terms, with 3,986 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible BNIP3L-associated GO terms across cancer lineages are Mitochondrial fragmentation involved in apoptotic process, Negative regulation of mitochondrial membrane potential, and Negative regulation of membrane potential. Each is linked with BNIP3L in more than 17 cancer types. Because this analysis shows association rather than direction, both BNIP3L-to-partner and partner-to-BNIP3L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial fragmentation involved in apoptotic process grouped by BNIP3L-low versus BNIP3L-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BNIP3L→partner) and Y-score (partner→BNIP3L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Mitochondrial fragmentation involved in apoptotic process →	+0.202	+1.213	<.001	<.001	3	18
LIVER	Negative regulation of mitochondrial membrane potential →	+0.275	+1.658	<.001	<.001	3	16
LIVER	Negative regulation of membrane potential →	+0.275	+1.658	<.001	<.001	3	16
LUNG_NSCLC_LUSC	Mitochondrial protein catabolic process →	+0.234	+1.488	<.001	<.001	3	15
STOMACH	Regulation of protein localization to mitochondrion →	+0.122	+1.471	<.001	<.001	3	12
LIVER	Positive regulation of cellular response to transforming growth factor beta stimulus →	+0.152	+1.974	<.001	.005	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,986 associations by consensus.

Mitochondrial fragmentation involved in apoptotic process by BNIP3L expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →