BMPER

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, BMPER mutation is significantly associated with the RNA expression of many other genes, with 138 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible BMPER-associated genes across cancer lineages are AVP, BANF2, and EIF3L. Each is linked with BMPER in more than 1 cancer types. Because this analysis shows association rather than direction, both BMPER-to-partner and partner-to-BMPER results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AVP grouped by BMPER-low versus BMPER-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BMPER→partner) and Y-score (partner→BMPER) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LymphomaAVP →+0.031+5.209<.001.00531
BLOOD_LymphomaBANF2 →+0.096+5.643<.001.00231
LARGE_INTESTINEEIF3L →+0.563+3.087.001.00631
LARGE_INTESTINESNU13 →+0.479+3.364.003.00231
LARGE_INTESTINEHSCB →+0.516+3.169.009.00931
LARGE_INTESTINEUSP14 →+0.643+3.087.004.00631
Each partner links to its Q-omics profile. Showing the 6 strongest of 138 associations by consensus.

AVP by BMPER expression — BLOOD_Lymphoma

Box plot of AVP in BMPER-low vs BMPER-high samples in BLOOD_Lymphoma.

Explore this box plot interactively →

Exploration