BMPER

Across TCGA pan-cancer cohorts, BMPER RNA differs between tumor and matched normal tissue in 15 of 18 cancer types tested, making tumor–normal expression one of BMPER’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where BMPER RNA is repressed in tumor relative to normal tissue. In most cancer types BMPER is over-expressed in tumor, although a few such as LUAD and BLCA show the opposite, repressed pattern.

LUAD, BLCA, and LUSC are the cancer types where BMPER tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in BMPER RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Female	III,IV	−2.217	<.001	11	view →
BLCA	All	IV	−1.020	.001	10	view →
LUSC	All	III,IV	−2.580	<.001	9	view →
LIHC	Male	III,IV	−2.270	<.001	9	view →
UCEC	All	All	−1.169	<.001	8	view →
COAD	All	III,IV	−0.653	<.001	8	view →
STAD	All	All	−1.109	<.001	7	view →
BRCA	All	II,III,IV	−1.525	<.001	6	view →
CHOL	Female	All	−1.533	<.001	5	view →
KICH	Female	All	−0.409	.004	4	view →
HNSC	Female	All	+0.441	.022	3	view →
PRAD	All	All	−0.678	.005	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 15 lineages.

BMPER–LUAD

Open the LUAD breakdown →