BMPER

Across TCGA pan-cancer cohorts, BMPER RNA is linked to patient survival in 27 of 34 cancer types, making it the most broadly survival-associated BMPER data layer compared with 11 for mutation status and 2 for mass-spec protein.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher BMPER RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated BMPER expression acts as an unfavorable survival marker, although some lineages such as PAAD and LAML show a favorable association.

OV, BLCA, and PAAD are the cancer types where BMPER RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	DFS	Quartile	II,III,IV	0.424	0.619	<.001	58	view →
BLCA	OS	Quartile	II,III,IV	0.297	0.553	.001	54	view →
PAAD	OS	Quartile	All	0.651	0.344	.001	43	view →
HNSC	OS	Tertile	All	0.582	0.722	.001	39	view →
LAML	DFS	Tertile	All	0.503	0.239	.005	32	view →
CESC	DFS	Median	III,IV	0.208	0.661	.004	20	view →
SKCM	OS	Tertile	IV	0.881	0.460	.001	18	view →
THCA	DFS	Median	III,IV	0.752	0.884	.013	15	view →
UCEC	DFS	Tertile	II,III,IV	0.887	0.773	.014	14	view →
MESO	OS	Quartile	III,IV	0.804	0.217	.017	12	view →
TGCT	DFS	Tertile	All	0.523	0.855	.003	12	view →
PRAD	DFS	Quartile	All	0.884	0.728	.006	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 27 lineages.

BMPER–OV (DFS)

Open the OV breakdown →