Across TCGA patient cohorts, BMP8A mutation is significantly associated with the RNA expression of many other genes, with 74 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BMP8A-associated genes across cancer lineages are RNU6-709P, RPS10P21, and RNU6-497P. Each is linked with BMP8A in more than 1 cancer types. Because this analysis shows association rather than direction, both BMP8A-to-partner and partner-to-BMP8A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BMP8A→partner) and Y-score (partner→BMP8A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU6-709P →	+0.421	+4.821	<.001	.003	3	2
UCEC	RPS10P21 →	+0.372	+2.939	<.001	.005	3	2
SKCM	RNU6-497P →	+0.348	+5.097	<.001	.008	3	2
UCEC	LINC01050 →	+0.353	+3.064	<.001	.005	3	1
UCEC	RPL23AP90 →	+0.405	+3.762	.006	.002	3	1
UCEC	OR6R2P →	+0.378	+2.798	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 74 associations by consensus.

Exploration

BMP8A survival (RNA) · tumor vs normal (RNA) · all BMP8A data types