BMERB1

Across TCGA patient cohorts, BMERB1 mutation is significantly associated with the RNA expression of many other genes, with 484 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BMERB1-associated genes across cancer lineages are GAPDHP56, OR5F2P, and RNU6-421P. Each is linked with BMERB1 in more than 1 cancer types. Because this analysis shows association rather than direction, both BMERB1-to-partner and partner-to-BMERB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GAPDHP56 grouped by BMERB1-low versus BMERB1-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BMERB1→partner) and Y-score (partner→BMERB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	GAPDHP56 →	+0.038	+6.569	<.001	.001	3	2
LGG	OR5F2P →	+0.076	+6.245	<.001	.001	3	2
LUAD	RNU6-421P →	+0.604	+5.984	<.001	.002	3	2
UCEC	RNU4-58P →	+0.206	+2.674	.002	.006	3	2
COAD	LINC01639 →	+0.472	+5.173	<.001	.001	3	2
CESC	NF1P6 →	+0.331	+6.342	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 484 associations by consensus.

GAPDHP56 by BMERB1 expression — CESC

Explore this box plot interactively →