BIVM-ERCC5

Across TCGA cell cohorts, BIVM-ERCC5 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible BIVM-ERCC5-associated genes across cancer lineages are FASLG and TAAR8. Each is linked with BIVM-ERCC5 in more than 1 cancer types. Because this analysis shows association rather than direction, both BIVM-ERCC5-to-partner and partner-to-BIVM-ERCC5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FASLG grouped by BIVM-ERCC5-low versus BIVM-ERCC5-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BIVM-ERCC5→partner) and Y-score (partner→BIVM-ERCC5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	FASLG →	+0.115	+4.044	<.001	.009	3	1
LUNG_NSCLC_LUAD	TAAR8 →	+0.022	+5.662	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

FASLG by BIVM-ERCC5 expression — LUNG_SCLC

Explore this box plot interactively →