BEX3

Across TCGA patient cohorts, BEX3 mutation is significantly associated with the RNA expression of many other genes, with 1,193 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BEX3-associated genes across cancer lineages are RNA5SP222, RNU7-176P, and RNU6-608P. Each is linked with BEX3 in more than 2 cancer types. Because this analysis shows association rather than direction, both BEX3-to-partner and partner-to-BEX3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP222 grouped by BEX3-low versus BEX3-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BEX3→partner) and Y-score (partner→BEX3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNA5SP222 →	+0.286	+7.731	<.001	.009	3	3
COAD	RNU7-176P →	+0.537	+7.741	<.001	.009	3	2
CESC	RNU6-608P →	+0.478	+4.409	<.001	.006	3	2
BRCA	RNA5SP100 →	+0.277	+8.055	<.001	.007	3	2
BLCA	BOD1P2 →	+0.130	+7.040	<.001	<.001	3	2
BLCA	GOLGA6L11P →	+0.140	+5.411	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,193 associations by consensus.

RNA5SP222 by BEX3 expression — BRCA

Explore this box plot interactively →