BEX3

Across TCGA cell cohorts, BEX3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,662 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible BEX3-associated GO terms across cancer lineages are Negative regulation of gene expression, epigenetic, Heterochromatin organization, and Respiratory electron transport chain. Each is linked with BEX3 in more than 9 cancer types. Because this analysis shows association rather than direction, both BEX3-to-partner and partner-to-BEX3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of gene expression, epigenetic grouped by BEX3-low versus BEX3-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BEX3→partner) and Y-score (partner→BEX3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Negative regulation of gene expression, epigenetic →	+0.065	+2.705	<.001	<.001	3	10
BLOOD_Lymphoma	Heterochromatin organization →	+0.066	+3.674	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Respiratory electron transport chain →	+0.077	+0.931	<.001	.007	3	10
KIDNEY	Negative regulation of post-translational protein modification →	+0.067	+0.596	.009	.008	3	10
BLOOD_Lymphoma	Transcription preinitiation complex assembly →	+0.072	+3.103	<.001	<.001	3	10
BLOOD_Leukemia	Protein insertion into ER membrane →	+0.043	+2.130	.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,662 associations by consensus.

Negative regulation of gene expression, epigenetic by BEX3 expression — BLOOD_Lymphoma

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