BDKRB2

Across TCGA patient cohorts, BDKRB2 mutation is significantly associated with the RNA expression of many other genes, with 2,936 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BDKRB2-associated genes across cancer lineages are EIF2B2, BPY2DP, and SCARNA21B. Each is linked with BDKRB2 in more than 2 cancer types. Because this analysis shows association rather than direction, both BDKRB2-to-partner and partner-to-BDKRB2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EIF2B2 grouped by BDKRB2-low versus BDKRB2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BDKRB2→partner) and Y-score (partner→BDKRB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EIF2B2 →	+0.442	+2.949	<.001	<.001	3	3
STAD	BPY2DP →	+0.304	+5.105	<.001	.008	3	3
READ	SCARNA21B →	+0.384	+5.039	<.001	.008	3	2
READ	RN7SL470P →	+0.168	+5.653	<.001	.003	3	2
UCEC	RN7SL248P →	+0.044	+2.783	<.001	.009	3	2
SKCM	DUSP14 →	+0.440	+1.813	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,936 associations by consensus.

EIF2B2 by BDKRB2 expression — UCEC

Explore this box plot interactively →