BCRP6

Across TCGA patient cohorts, BCRP6 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,752 significant associations in total. STAD shows the largest number of these associations.

The most reproducible BCRP6-associated GO terms across cancer lineages are Peptidyl-L-cysteine S-palmitoylation, Positive regulation of sphingolipid biosynthetic process, and Mitochondrial outer membrane permeabilization. Each is linked with BCRP6 in more than 5 cancer types. Because this analysis shows association rather than direction, both BCRP6-to-partner and partner-to-BCRP6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Peptidyl-L-cysteine S-palmitoylation grouped by BCRP6-low versus BCRP6-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BCRP6→partner) and Y-score (partner→BCRP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Peptidyl-L-cysteine S-palmitoylation →	+0.026	+0.023	<.001	.002	3	5
GBM	Positive regulation of sphingolipid biosynthetic process →	+0.030	+0.063	.002	<.001	3	5
STAD	Mitochondrial outer membrane permeabilization →	+0.030	+0.027	<.001	<.001	3	4
STAD	Establishment of cell polarity →	+0.031	+0.026	<.001	<.001	3	4
GBM	Myelin assembly →	+0.037	+0.071	.001	<.001	3	4
STAD	Establishment or maintenance of cell polarity →	+0.029	+0.024	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,752 associations by consensus.

Peptidyl-L-cysteine S-palmitoylation by BCRP6 expression — STAD

Explore this box plot interactively →