BCRP6

Across TCGA pan-cancer cohorts, BCRP6 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of BCRP6’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where BCRP6 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types BCRP6 is over-expressed in tumor.

LUSC are the cancer types where BCRP6 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in BCRP6 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	All	II,III,IV	+0.035	.017	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 1 strongest of 1 lineages.

BCRP6–LUSC

Open the LUSC breakdown →