Across TCGA patient cohorts, BCR RNA expression is significantly associated with the protein abundance of many other proteins, with 10,896 significant associations in total. GBM shows the largest number of these associations.

The most reproducible BCR-associated proteins across cancer lineages are BCR_S122, BCR_S473, and SPTBN2. Each is linked with BCR in more than 6 cancer types. Because this analysis shows association rather than direction, both BCR-to-partner and partner-to-BCR results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (BCR→partner) and Y-score (partner→BCR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	BCR_S122 →	+0.547	+0.593	<.001	<.001	3	7
BRCA	BCR_S473 →	+0.754	+0.651	<.001	<.001	3	5
GBM	SPTBN2 →	+0.481	+0.500	<.001	.004	3	4
HNSC	KIAA1671 →	+0.392	+0.867	<.001	<.001	3	4
GBM	ARVCF →	+0.450	+0.817	<.001	<.001	3	4
LSCC	BCR_S354 →	+0.719	+0.582	.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,896 associations by consensus.

Exploration

BCR survival (RNA) · tumor vs normal (RNA) · all BCR data types